Background: Current diagnostic systems for neurodevelopmental disorders do not have clear links to underlying neurobiology, limiting their utility in identifying targeted treatments for individuals.Here, we aimed to investigate differences in functional brain network integrity between traditional diagnostic categories (autism spectrum disorder [ASD

The need to orient the family on the development of the pre-school girl and boy skill in conversation and the inadequacies in the theoretical and methodological order to conceive the developing educational process, in the conditions of the home, are the motives that lead to the elaboration of a proposal for family orientation activities aimed at th

Considering that the precise delivery of Celastrol (Cst) into mitochondria to induce mitochondrial dysfunction may be a potential approach to improve the therapeutic outcomes of Cst on TNBC, a novel tumor mitochondria dual-targeted mixed-micelle nano-system was fabricated via self-synthesized triphenylphosphonium-modified cholesterol (TPP-Chol) and

Allergic diseases have become a primary public health issue in a moderately prosperous society.Colonization of microorganisms early in life appears to be significant in guiding the regulation of childhood immune system maturation and allergy development.Since the oral cavity is the first position where most foreign antigens meet the immune system,

Xiaoling Cai,1 Fang Zhang,1 Chu Lin,1 Xiaomei Zhang,2 Zhufeng Wang,3 Huifang Xing,4 Lin Nie,5 Xueyao Han,1 Linong Ji1 1Department of Endocrinology and Metabolism, Peking University People’s Hospital, Beijing, People’s Republic of China; 2Department of Endocrinology and Metabolism, Peking University Appliance Paint International Hospital